| 6:00 pm | Kirkwood-28 at CBC-26 - Final | 28-26 |
| 6:00 pm | MICDS-38 at Hazelwood East-14 - Final | 38-14 |
| 6:00 pm | Orchard Farm-14 at Parkway North-46 - Final | 46-14 |
| 6:00 pm | Miller Career-0 at Lutheran North-80 - Final | 80-0 |
| 6:00 pm | Lincoln-Way Central-28 at Bradley-Bourbonnais-16 - Final | 28-16 |
| 7:00 pm | Ash Grove-0 at Adrian-27 - Final | 27-0 |
| 7:00 pm | Caruthersville-21 at Valle Catholic-63 - Final | 63-21 |
| 7:00 pm | Tolton Catholic-34 at Lafayette County-82 - Final | 82-34 |
| 7:00 pm | Charleston-34 at Crystal City-36 - Final | 36-34 |
| 7:00 pm | Lamar-15 at Warsaw-13 - Final | 15-13 |
| 7:00 pm | Lebanon-18 at Helias-30 - Final | 30-18 |
| 7:00 pm | Mid-Buchanan-26 at Brookfield-14 - Final | 26-14 |
| 7:00 pm | Warrensburg-38 at Pleasant Hill-35 - Final | 38-35 |
| 7:00 pm | Oak Park-21 at Park Hill-31 - Final | 31-21 |
| 7:00 pm | Salisbury-6 at Tipton-42 - Final | 42-6 |
| 7:00 pm | West Platte-23 at Hamilton-33 - Final | 33-23 |
| 7:00 pm | Perryville-0 at Festus-43 - Final | 43-0 |
| 7:00 pm | Monroe City-0 at South Shelby-6 - Final | 6-0 |
| 7:00 pm | Joplin-21 at Nixa-48 - Final | 48-21 |
| 7:00 pm | Rock Bridge-43 at Troy Buchanan-19 - Final | 43-19 |
| 7:00 pm | Pierce City-7 at Marionville-26 - Final | 26-7 |
| 7:00 pm | Harrisburg, Missouri-14 at Westran-10 - Final | 14-10 |
| 7:00 pm | Savannah-7 at Kearney-34 - Final | 34-7 |
| 7:00 pm | Forsyth-7 at Seneca-64 - Final | 64-7 |
| 7:00 pm | Boonville-6 at Blair Oaks-49 - Final | 49-6 |
| 7:00 pm | Bolivar-21 at West Plains-24 - Final | 24-21 |
| 7:00 pm | Mount Vernon-28 at Strafford-21 - Final | 28-21 |
| 7:00 pm | Lincolnshire Stevenson-0 at Lincoln-Way East-45 - Final | 45-0 |
| 7:00 pm | Jackson-49 at Seckman-28 - Final | 49-28 |
| 7:00 pm | Republic-35 at Branson-10 - Final | 35-10 |
| 7:00 pm | Lee's Summit-15 at Lee's Summit North-29 - Final | 29-15 |
| 7:00 pm | Naperville Central-24 at LaGrange Lyons-7 - Final | 24-7 |
| 7:00 pm | SLUH-0 at De Smet-35 - Final | 35-0 |
| 7:00 pm | Washington-7 at Lafayette-42 - Final | 42-7 |
| 7:00 pm | Liberty (KC)-28 at Blue Springs South-7 - Final | 28-7 |
| 7:00 pm | Oak Grove-0 at Odessa-48 - Final | 48-0 |
| 7:00 pm | Pacific-14 at Gateway STEM-28 - Final | 28-14 |
| 7:00 pm | KIPP Kansas City Legacy-6 at Pembroke Hill-36 - Final | 36-6 |
| 7:00 pm | Hallsville-37 at Moberly-35 - Final | 37-35 |
| 7:00 pm | Mountain View-Liberty-14 at Fair Grove-42 - Final | 42-14 |
| 7:00 pm | Hannibal-28 at Warrenton-42 - Final | 42-28 |
| 7:00 pm | Webb City-42 at Carthage-28 - Final | 42-28 |
| 7:00 pm | Bowling Green-28 at Hermann-20 - Final | 28-20 |
| 7:00 pm | North Platte-15 at Putnam County, Mo.-14 - Final | 15-14 |
| 7:00 pm | Cape Girardeau Central-14 at Cardinal Ritter-56 - Final | 56-14 |
| 7:00 pm | St. Pius X (Kansas City)-23 at Platte County-45 - Final | 45-23 |
| 7:00 pm | Ste. Genevieve-13 at Dexter-28 - Final | 28-13 |
| 7:00 pm | Fort Zumwalt West-45 at North Point-8 - Final | 45-8 |
| 7:00 pm | Cameron-42 at Maryville-49 - Final | 49-42 |
| 7:30 pm | Gurnee Warren-15 at Elmhurst York-34 - Final | 34-15 |