| 12:00 am | Grandview-39 at Bourbon-24 - Final | 39-24 |
| 4:30 pm | Nerinx Hall-34 at Ursuline-68 - Final | 68-34 |
| 4:30 pm | Lafayette-38 at Kirkwood-53 - Final | 53-38 |
| 5:00 pm | Perryville-47 at Meadow Heights-49 - Final | 49-47 |
| 5:00 pm | Soldan-24 at Medicine and Bioscience-62 - Final | 62-24 |
| 5:30 pm | Gateway STEM vs Sumner at Soldan | Rivalry |
| 5:30 pm | Sullivan-28 at St. James-56 - Final | 56-28 |
| 5:30 pm | Hazelwood Central-50 at Seckman-53 - Final | 53-50 |
| 5:30 pm | Valley Park-51 at Brentwood-56 - Final | 56-51 |
| 5:30 pm | Pacific-42 at St. Clair-55 - Final | 55-42 |
| 5:30 pm | Fox-26 at Hazelwood West-72 - Final | 72-26 |
| 5:45 pm | Westminster-51 at Clayton-53 - Final | 53-51 |
| 6:00 pm | Northwest Cedar Hill-41 at Parkway North-77 - Final | 77-41 |
| 6:00 pm | Cor Jesu-24 at Incarnate Word-81 - Final | 81-24 |
| 6:00 pm | Oakville-47 at Ladue-52 - Final | 52-47 |
| 6:00 pm | Steeleville-35 at Marissa-52 - Final | 52-35 |
| 6:00 pm | St. Pius X-21 at Cardinal Ritter-65 - Final | 65-21 |
| 6:00 pm | Chester-49 at Sparta-39 - Final | 49-39 |
| 6:00 pm | Dupo-27 at Gibault-43 - Final | 43-27 |
| 6:00 pm | Home School-11 vs Whitfield-53 at Whitfield - Final | 53-11 |
| 6:00 pm | Notre Dame-52 at Affton-14 - Final | 52-14 |
| 6:30 pm | Jefferson-64 at Visitation-66 - Final | 66-64 |
| 7:00 pm | Windsor (Imperial)-51 at Festus-74 - Final | 74-51 |
| 7:00 pm | De Soto-31 at Hillsboro-60 - Final | 60-31 |
| 7:00 pm | Crystal City-41 at Herculaneum-45 - Final | 45-41 |
| 7:00 pm | Clopton-89 at Wright City-38 - Final | 89-38 |
| 7:00 pm | Hermann-57 at Union-53 - Final | 57-53 |
| 7:15 pm | Owensville-49 at New Haven-24 - Final | 49-24 |
| 7:15 pm | Freeburg-25 at Breese Central-58 - Final | 58-25 |
| 7:30 pm | Father McGivney-35 at Rochester-28 - Final | 35-28 |
| 7:30 pm | Edwardsville-79 at Belleville West-14 - Final | 79-14 |
| 7:30 pm | Belleville East-54 at East St. Louis-31 - Final | 54-31 |
| 7:30 pm | Centralia, Illinois at Marion | Rivalry |
| 7:30 pm | Collinsville-27 at Alton-67 - Final | 67-27 |
| 7:30 pm | Salem, Illinois-69 at Wood River-53 - Final | 69-53 |
| 7:30 pm | Carlyle-60 at Red Bud-26 - Final | 60-26 |
| 7:30 pm | Christ Our Rock at Metro-East Lutheran | Rivalry |
| 7:30 pm | Columbia-45 at Roxana-28 - Final | 45-28 |
| 7:30 pm | Okawville-51 at Wesclin-21 - Final | 51-21 |