| Time | Event | Score |
|---|
| 6:00 pm | Rockhurst-21 at SLUH-11 - Final | 21-11 |
| 6:00 pm | Parkway West-7 at Hazelwood East-48 - Final | 48-7 |
| 6:00 pm | St. Mary's-3 at CBC-49 - Final | 49-3 |
| 6:00 pm | Summit-30 at Ritenour-24 - Final | 30-24 |
| 6:30 pm | LaSalle-Peru-19 at O'Fallon-24 - Final | 24-19 |
| 6:30 pm | Rock Bridge-28 at Francis Howell-21 - Final | 28-21 |
| 7:00 pm | Brookfield-42 at Marceline-0 - Final | 42-0 |
| 7:00 pm | North Platte-14 at West Platte-28 - Final | 28-14 |
| 7:00 pm | Warrensburg-41 at Oak Grove-0 - Final | 41-0 |
| 7:00 pm | Carl Junction-27 at West Plains-34 - Final | 34-27 |
| 7:00 pm | Republic-35 at Willard-7 - Final | 35-7 |
| 7:00 pm | Fulton-22 at Duchesne-6 - Final | 22-6 |
| 7:00 pm | Chillicothe-13 at St. Joseph Benton-27 - Final | 27-13 |
| 7:00 pm | Lindbergh-56 at Mehlville-21 - Final | 56-21 |
| 7:00 pm | Anna-Jonesboro-6 at Carterville-54 - Final | 54-6 |
| 7:00 pm | Cahokia-14 at Sycamore-52 - Final | 52-14 |
| 7:00 pm | Virden North Mac-8 at Greenville-17 - Final | 17-8 |
| 7:00 pm | KC Northeast-58 at Harmon, Kan.-6 - Final | 58-6 |
| 7:00 pm | Farmington-42 at Park Hills Central-28 - Final | 42-28 |
| 7:00 pm | North Kansas City-0 at Liberty (KC)-42 - Final | 42-0 |
| 7:00 pm | Windsor (Imperial)-24 at Bayless-8 - Final | 24-8 |
| 7:00 pm | University Academy-20 at Cameron-42 - Final | 42-20 |
| 7:00 pm | Piasa Southwestern-41 at Hillsboro, Illinois-40 - Final | 41-40 |
| 7:00 pm | Wood River-32 at Red Bud-46 - Final | 46-32 |
| 7:00 pm | Scott City-7 at Dexter-62 - Final | 62-7 |
| 7:00 pm | Webster Groves-0 at Seckman-28 - Final | 28-0 |
| 7:00 pm | Mountain Grove-26 at Thayer-7 - Final | 26-7 |
| 7:00 pm | Jerseyville-14 at Columbia-21 - Final | 21-14 |
| 7:00 pm | Nixa-42 at Glendale-0 - Final | 42-0 |
| 7:00 pm | Lafayette-38 at Marquette-16 - Final | 38-16 |
| 7:00 pm | Montgomery County-32 at Louisiana-14 - Final | 32-14 |
| 7:00 pm | Cole Camp-6 at Adrian-48 - Final | 48-6 |
| 7:00 pm | Veritas Christian-13 at Winfield-48 - Final | 48-13 |
| 7:00 pm | KIPP Kansas City-22 at Lone Jack-6 - Final | 22-6 |
| 7:00 pm | East Newton-35 at McDonald County-33 - Final | 35-33 |
| 7:00 pm | Lift for Life-12 at Helias-17 - In Progress | 17-12 |
| 7:00 pm | Clinton-40 at Kansas City Center-0 - Final | 40-0 |
| 7:00 pm | Eureka-63 at Pattonville-28 - Final | 63-28 |
| 7:00 pm | Kennett-0 at Cape Girardeau Central-56 - Final | 56-0 |
| 7:00 pm | Cabool-6 at Salem-36 - Final | 36-6 |
| 7:00 pm | Eldon-21 at Boonville-46 - Final | 46-21 |
| 7:00 pm | El Dorado Springs-0 at Butler-42 - Final | 42-0 |
| 7:00 pm | Alton Marquette-0 at Roxana-42 - Final | 42-0 |
| 7:00 pm | Sherwood-30 at Versailles-6 - Final | 30-6 |
| 7:00 pm | Marshfield-46 at Springfield Central-0 - Final | 46-0 |
| 7:00 pm | Herculaneum-6 at De Soto-43 - Final | 43-6 |
| 7:00 pm | Blue Springs South-37 at Lee's Summit West-0 - Final | 37-0 |
| 7:00 pm | Blair Oaks-42 at Southern Boone-0 - Final | 42-0 |
| 7:00 pm | Mountain View-Liberty-6 at Houston-0 - Final | 6-0 |
| 7:00 pm | Carlinville-40 at Gillespie-3 - Final | 40-3 |
| 7:00 pm | Hogan Prep-12 at Summit Christian-27 - Final | 27-12 |
| 7:00 pm | Staunton-0 at Pana-42 - Final | 42-0 |
| 7:00 pm | Skyline-12 at Diamond-30 - Final | 30-12 |
| 7:00 pm | Springfield Hillcrest-0 at Branson-49 - Final | 49-0 |
| 7:00 pm | Mount Vernon, Illinois-32 at Alton-33 - Final | 33-32 |
| 7:00 pm | Raytown South-26 at Grandview K.C.-13 - Final | 26-13 |
| 7:00 pm | Decatur St. Teresa-7 at Highland-55 - Final | 55-7 |
| 7:00 pm | Kirksville-41 at Centralia, Mo.-12 - Final | 41-12 |
| 7:00 pm | Bowling Green-64 at Mark Twain-12 - Final | 64-12 |
| 7:00 pm | Joplin-43 at Webb City-42 - Final | 43-42 |
| 7:00 pm | Bridgeport Red Hill-22 at Carlyle-20 - Final | 22-20 |
| 7:00 pm | Dwight-21 at Ottawa Marquette-20 - Final | 21-20 |
| 7:00 pm | Mattoon-34 at Marion-55 - Final | 55-34 |
| 7:00 pm | North Point-35 at St. Charles-22 - Final | 35-22 |
| 7:00 pm | Windsor (Sedalia)-51 at Crest Ridge-16 - Final | 51-16 |
| 7:00 pm | Ruskin-20 at Belton-27 - Final | 27-20 |
| 7:00 pm | Ladue-10 at Fox-27 - Final | 27-10 |
| 7:00 pm | Raymore-Peculiar-22 at Staley-31 - Final | 31-22 |
| 7:00 pm | Dupo-7 at Nashville-48 - Final | 48-7 |
| 7:00 pm | Highland, Missouri-16 at Clark County-40 - Final | 40-16 |
| 7:00 pm | Reeds Spring-28 at Hollister-40 - Final | 40-28 |
| 7:00 pm | Hazelwood West-28 at Parkway South-31 - Final | 31-28 |
| 7:00 pm | South Callaway-12 at Tipton-46 - Final | 46-12 |
| 7:00 pm | Maryville-42 at St. Joseph Lafayette-0 - Final | 42-0 |
| 7:00 pm | Pontiac-20 at Civic Memorial-14 - Final | 20-14 |
| 7:00 pm | Gallatin-8 at South Harrison-48 - Final | 48-8 |
| 7:00 pm | Fort Zumwalt East-27 at Francis Howell North-20 - Final | 27-20 |
| 7:00 pm | Lutheran North-50 at Cardinal Ritter-48 - Final | 50-48 |
| 7:00 pm | Richmond-48 at Lexington-22 - Final | 48-22 |
| 7:00 pm | Perryville-38 at Cuba-14 - Final | 38-14 |
| 7:00 pm | Cassville-21 at Aurora-11 - Final | 21-11 |
| 7:00 pm | Springfield Catholic-33 at Clever-7 - Final | 33-7 |
| 7:00 pm | Mount Zion-56 at Mater Dei-37 - Final | 56-37 |
| 7:00 pm | Collinsville-34 at Triad-17 - Final | 34-17 |
| 7:00 pm | Grain Valley-53 at Truman-0 - Final | 53-0 |
| 7:00 pm | Linn-0 at Harrisburg, Missouri-51 - Final | 51-0 |
| 7:00 pm | Ozark-9 at Kickapoo-14 - Final | 14-9 |
| 7:00 pm | St. James-20 at Pacific-56 - Final | 56-20 |
| 7:00 pm | Centralia, Illinois-35 at Effingham-19 - Final | 35-19 |
| 7:00 pm | Logan-Rogersville-28 at Bolivar-49 - Final | 49-28 |
| 7:00 pm | Putnam County, Mo.-22 at Milan-28 - Final | 28-22 |
| 7:00 pm | Chaminade-21 at Hickman-28 - Final | 28-21 |
| 7:00 pm | St. Charles West-7 at Potosi-19 - Final | 19-7 |
| 7:00 pm | Macon-10 at Monroe City-44 - Final | 44-10 |
| 7:00 pm | Waynesville-20 at Lebanon-64 - Final | 64-20 |
| 7:00 pm | Park Hill South-34 at St. Joseph Central-16 - Final | 34-16 |
| 7:00 pm | Carrollton-12 at Lafayette County-48 - Final | 48-12 |
| 7:00 pm | Principia-7 at Lutheran South-42 - Final | 42-7 |
| 7:00 pm | West Frankfort-50 at Sparta-14 - Final | 50-14 |
| 7:00 pm | Cass Midway-36 at Lincoln-8 - Final | 36-8 |
| 7:00 pm | Lawson-49 at Lathrop-0 - Final | 49-0 |
| 7:00 pm | De Smet-42 at Edwardsville-19 - Final | 42-19 |
| 7:00 pm | Mid-Buchanan-7 at East Buchanan-3 - Final | 7-3 |
| 7:00 pm | Du Quoin-14 at Murphysboro-28 - Final | 28-14 |
| 7:00 pm | Fort Osage-59 at William Chrisman-6 - Final | 59-6 |
| 7:00 pm | Lamar-7 at Seneca-57 - Final | 57-7 |
| 7:00 pm | Benton, Illinois-34 at Harrisburg, Illinois-7 - Final | 34-7 |
| 7:00 pm | Troy Buchanan-49 at Battle-28 - Final | 49-28 |
| 7:00 pm | McCluer North-0 at Parkway Central-40 - Final | 40-0 |
| 7:00 pm | Hamilton-35 at Trenton-13 - Final | 35-13 |
| 7:00 pm | Normal Community West-64 at Urbana-0 - Final | 64-0 |
| 7:00 pm | Vianney-35 at Belleville West-27 - Final | 35-27 |
| 7:00 pm | St. Vincent-51 at Jefferson-35 - Final | 51-35 |
| 7:00 pm | Hayti-46 at Malden-22 - Final | 46-22 |
| 7:00 pm | Neosho-20 at Carthage-42 - Final | 42-20 |
| 7:00 pm | Lee's Summit North-29 at Lee's Summit-28 - Final | 29-28 |
| 7:00 pm | Grandview-33 at Crystal City-40 - Final | 40-33 |
| 7:00 pm | Marionville-24 at Miller-7 - Final | 24-7 |
| 7:00 pm | Carbondale-38 at Mascoutah-42 - Final | 42-38 |
| 7:00 pm | Smithville-43 at Winnetonka-7 - Final | 43-7 |
| 7:00 pm | Polo-42 at Maysville-8 - Final | 42-8 |
| 7:00 pm | Warrenton-42 at Fort Zumwalt South-6 - Final | 42-6 |
| 7:00 pm | Ash Grove-20 at Sarcoxie-18 - Final | 20-18 |
| 7:00 pm | Moberly-35 at Orchard Farm-36 - Final | 36-35 |
| 7:00 pm | Parkview-18 at Rolla-48 - Final | 48-18 |
| 7:00 pm | Van Horn-26 at Pembroke Hill-43 - Final | 43-26 |
| 7:00 pm | Oak Park-15 at Park Hill-45 - Final | 45-15 |
| 7:00 pm | Breese Central-50 at Herrin-6 - Final | 50-6 |
| 7:00 pm | Nevada-21 at Pleasant Hill-46 - Final | 46-21 |
| 7:00 pm | Festus-7 at Jackson-43 - Final | 43-7 |
| 7:00 pm | Holden-39 at Knob Noster-36 - Final | 39-36 |
| 7:00 pm | St. Pius X (Kansas City)-49 at Savannah-21 - Final | 49-21 |
| 7:00 pm | Osage-0 at Borgia-24 - Final | 24-0 |
| 7:00 pm | Wesclin-41 at Madison, Illinois-26 - Final | 41-26 |
| 7:00 pm | Vandalia-54 at Litchfield-25 - Final | 54-25 |
| 7:00 pm | Charleston, Illinois-10 at Salem, Illinois-35 - Final | 35-10 |
| 7:00 pm | Fredericktown-0 at East Prairie-39 - Final | 39-0 |
| 7:00 pm | Forsyth-41 at Buffalo-6 - Final | 41-6 |
| 7:00 pm | IMG Academy (Fla.)-14 at East St. Louis-13 - Final | 14-13 |
| 7:00 pm | Mount Vernon-48 at Monett-56 - Final | 56-48 |
| 7:00 pm | MICDS-45 at Mexico-7 - Final | 45-7 |
| 7:00 pm | Liberty (Wentzville)-35 at Holt-7 - Final | 35-7 |
| 7:00 pm | Fayette-34 at Russellville-28 - Final | 34-28 |
| 7:00 pm | KC Southeast-70 at Camdenton-0 - Final | 70-0 |
| 7:00 pm | Fort Zumwalt West-17 at Hannibal-20 - Final | 20-17 |
| 7:00 pm | St. Michael the Archangel-28 at Tolton Catholic-29 - Final | 29-28 |
| 7:00 pm | Kelly-48 at Chaffee-0 - Final | 48-0 |
| 7:00 pm | Liberty North-31 at Blue Springs-21 - Final | 31-21 |
| 7:00 pm | Granite City-0 at Belleville East-71 - Final | 71-0 |
| 7:00 pm | Raytown-13 at Platte County-55 - Final | 55-13 |
| 7:00 pm | Poplar Bluff-36 at Hillsboro-28 - Final | 36-28 |
| 7:00 pm | Ste. Genevieve-20 at Caruthersville-42 - Final | 42-20 |
| 7:00 pm | Salisbury-14 at Westran-26 - Final | 26-14 |
| 7:00 pm | Kearney-56 at Excelsior Springs-0 - Final | 56-0 |
| 7:00 pm | Sikeston-14 at Charleston-32 - Final | 32-14 |
| 7:00 pm | Smith-Cotton-41 at Marshall-0 - Final | 41-0 |
| 7:00 pm | Valle Catholic-47 at St. Pius X-20 - Final | 47-20 |
| 7:00 pm | Palmyra-0 at South Shelby-44 - Final | 44-0 |
| 7:00 pm | Strafford-11 at Fair Grove-26 - Final | 26-11 |
| 7:00 pm | Priory-21 at Freeburg-55 - Final | 55-21 |
| 7:00 pm | Warsaw-68 at Pleasant Hope-8 - Final | 68-8 |
| 7:00 pm | Northwest Cedar Hill-31 at Oakville-27 - Final | 31-27 |
| 7:00 pm | North Callaway-46 at Wright City-42 - Final | 46-42 |
| 7:00 pm | Odessa-28 at Harrisonville-25 - Final | 28-25 |
| 7:00 pm | Hallsville-36 at California-42 - Final | 42-36 |
| 7:00 pm | Union-13 at Hermann-21 - Final | 21-13 |
| 7:00 pm | Quincy-41 at Capital City-32 - Final | 41-32 |
| 7:00 pm | Massac County-14 at Pinckneyville-28 - Final | 28-14 |
| 7:30 pm | Chicago Brother Rice-24 at Chicago St. Ignatius-7 - Final | 24-7 |